Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638316 | 1.00 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| SCHEMBL10332443 | 1.00 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| Hydrochloric Acid SCHEMBL9638288 | 0.99 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| Hydrochloric Acid SCHEMBL10332231 | 0.99 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| Hydrochloric Acid SCHEMBL9638281 | 0.99 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| Hydrochloric Acid SCHEMBL9638076 | 0.99 | TYMS (0.40) | TYMSNTSR2NTSR1P2RY6P2RY14 | |
| SCHEMBL10332186 | 0.92 | P2RY6 (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL10332184 | 0.92 | P2RY6 (0.44) | P2RY6P2RY14NT5E | |
| Hydrochloric Acid SCHEMBL9636947 | 0.91 | P2RY6 (0.43) | P2RY6P2RY14NT5E | |
| Hydrochloric Acid SCHEMBL9636952 | 0.91 | P2RY6 (0.43) | P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | disclosed |