Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | RAB9A | P51151 | 2/20 | 0.84 |
| ▸ | NPC1 | O15118 | 1/20 | 0.84 |
| ▸ | ATM | Q13315 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638535 | 0.95 | GAA (0.84) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9638547 | 0.91 | GAA (1.00) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9638183 | 0.91 | GAA (1.00) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9637241 | 0.88 | GAA (0.80) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9637329 | 0.88 | GAA (0.84) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9637318 | 0.79 | GAA (0.68) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9638260 | 0.78 | GAA (0.73) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9743642 | 0.77 | GAA (0.69) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9638267 | 0.76 | GAA (0.67) | GAAMAPTRAB9ANPC1ATM | |
| SCHEMBL9637298 | 0.75 | GAA (0.67) | GAAMAPTRAB9ANPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137904-A | Useful in the treatment of atherosclerosis and thrombosis | G. D. SEARLE & CO. (US) | 1992-08-11 | — | — | US | disclosed |