Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637933 | 0.86 | MAPT (0.36) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9638282 | 0.75 | — | — | |
| SCHEMBL1826724 | 0.75 | PTGDR2 (0.33) | MAPTALOX15 | |
| SCHEMBL10659842 | 0.75 | KDM4E (0.30) | MAPTALOX15 | |
| SCHEMBL10661289 | 0.75 | KDM4E (0.30) | MAPTALOX15 | |
| SCHEMBL3788910 | 0.75 | KDM4E (0.30) | MAPTALOX15 | |
| SCHEMBL10657572 | 0.73 | — | — | |
| SCHEMBL10576170 | 0.73 | — | — | |
| SCHEMBL9637945 | 0.73 | TDP1 (0.34) | VCAM1 | |
| SCHEMBL10657582 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0440809-A1 | METHYLENEDIPHOSPHONIC ACID COMPOUND AND ANTI-INFLAMMATORY CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 1991-08-14 | — | — | EP | disclosed |