Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norfenefrine SCHEMBL15485360 | 1.00 | HIF1A (0.59) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL29394995 | 1.00 | HIF1A (0.59) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL1797532 | 1.00 | HIF1A (0.59) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL30389272 | 1.00 | HIF1A (0.59) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL153494 | 1.00 | HIF1A (0.59) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL1650723 | 0.98 | HIF1A (0.61) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norfenefrine SCHEMBL217926 | 0.98 | HIF1A (0.61) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| Norepinephrine SCHEMBL2838434 | 0.89 | BLM (0.77) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| SCHEMBL2150842 | 0.84 | HIF1A (0.56) | HIF1ANFKB1ADRB1ADRA1ATSHR | |
| SCHEMBL17735450 | 0.84 | HIF1A (0.56) | HIF1ANFKB1ADRB1ADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120746-A | Inhibit gastric acid secretion | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| US-4923882-A | Novel amine derivatives, salts thereof and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | disclosed |