Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 14/20 | 0.56 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639830 | 0.82 | TSHR (0.53) | PDE7APDE7BTSHRMEN1KMT2A | |
| SCHEMBL6516022 | 0.80 | PDE7A (0.65) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL11603010 | 0.79 | PDE7A (0.63) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL8669659 | 0.77 | PDE7A (0.61) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL27875198 | 0.77 | PDE7A (0.61) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL21444960 | 0.73 | PDE7A (0.60) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL6556635 | 0.73 | PDE7A (0.57) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL6102170 | 0.72 | TP53 (0.42) | TSHRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8884363 | 0.72 | PDE7A (1.00) | PDE7APDE7BPDE4BPDE4DPOLB | |
| SCHEMBL1524058 | 0.72 | MAPK1 (0.72) | PDE7APDE7BPDE4BPDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |