Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | TK2 | O00142 | 4/20 | 0.61 |
| ▸ | TK1 | P04183 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639852 | 1.00 | ABCG2 (0.67) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL19983719 | 0.91 | ABCG2 (0.64) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL2056737 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL1145611 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5360915 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5372686 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5360913 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5367768 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5358026 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL22875462 | 0.89 | ABCG2 (0.67) | ABCG2ABCB1TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153180-A | Used for treating aids | BURROUGHS WELLCOME CO. | 1992-10-06 | — | — | US | disclosed |
| US-4963662-A | Fluorinated nucleosides and method for treating retrovirus infections therewith | AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) | 1990-10-16 | — | — | US | disclosed |