Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640317 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9641109 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9640293 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL10335486 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9641141 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9640149 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9640150 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9641559 | 1.00 | RARB (0.53) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL9641121 | 0.99 | RARB (0.52) | RARBRARARARGMAPTMEN1 | |
| SCHEMBL10335713 | 0.97 | RARB (0.50) | RARBRARARARGMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357702-B1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0357702-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989006678-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-07-27 | — | — | WO | disclosed |