Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640482 | 1.00 | CYP1A2 (0.59) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL28747674 | 0.92 | CYP1A2 (0.59) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL29702447 | 0.92 | CYP1A2 (0.59) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640497 | 0.90 | CYP1A2 (0.57) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL28747688 | 0.87 | CYP1A2 (0.54) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640108 | 0.86 | CYP1A2 (0.56) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640088 | 0.86 | CYP1A2 (0.56) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640818 | 0.85 | HSD17B10 (0.75) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640864 | 0.85 | MEN1 (0.56) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL9640845 | 0.85 | MEN1 (0.56) | CYP1A2HSD17B10CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287909-B1 | AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR | SALUTAR, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |