Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | VHL | P40337 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739643 | 1.00 | POLB (0.69) | POLBPTPN1MEN1KMT2AAPOBEC3A | |
| SCHEMBL7173956 | 1.00 | POLB (0.69) | POLBPTPN1MEN1KMT2AAPOBEC3A | |
| SCHEMBL16857492 | 0.89 | POLB (0.56) | POLBPTPN1MEN1KMT2ANPSR1 | |
| SCHEMBL16857494 | 0.89 | POLB (0.56) | POLBPTPN1MEN1KMT2ANPSR1 | |
| SCHEMBL16857495 | 0.89 | POLB (0.56) | POLBPTPN1MEN1KMT2ANPSR1 | |
| SCHEMBL7309265 | 0.87 | POLB (0.65) | POLBMEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL20179 | 0.86 | POLB (0.64) | POLBMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL636506 | 0.86 | POLB (0.64) | POLBMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL636507 | 0.86 | POLB (0.64) | POLBMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4251706 | 0.86 | POLB (0.64) | POLBMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |