Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15108582 | 0.76 | KDM4E (0.62) | KDM4EHPGDHSD17B10USP2NPSR1 | |
| SCHEMBL27452629 | 0.74 | HCRTR1 (0.50) | KDM4EHPGDHSD17B10USP2NPSR1 | |
| SCHEMBL20976824 | 0.74 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL29117985 | 0.73 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL21963537 | 0.73 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL5383937 | 0.72 | HTR2C (0.35) | HPGDNPSR1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29367258 | 0.72 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL27452742 | 0.72 | KDM4E (0.45) | KDM4EHPGDHSD17B10USP2NPSR1 | |
| Hydrochloric Acid SCHEMBL15796256 | 0.72 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL22018203 | 0.71 | KDM4E (0.44) | KDM4EHPGDHSD17B10USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-101938988-B | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| CN-101938988-A | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2011-01-05 | — | — | CN | disclosed |
| EP-2250998-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | KDM4E 2446/4885HPGD 1727/4885HSD17B10 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.