Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643113 | 1.00 | CCNB2 (0.35) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9642340 | 0.94 | CCNB2 (0.38) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9641878 | 0.87 | CCNB2 (0.36) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9643518 | 0.87 | CCNB2 (0.36) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL10705541 | 0.86 | CCNB2 (0.42) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9643461 | 0.84 | CCNB2 (0.35) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9641661 | 0.84 | CCNB2 (0.35) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9643144 | 0.80 | PPARG (0.36) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9643118 | 0.80 | PPARG (0.36) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL9641640 | 0.79 | KDM4E (0.35) | ALOX15HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |