Zinc Ion

Zinc Ion

SCHEMBL964381

CCSCC(=O)[O-].CCSCC(=O)[O-].[Zn+2]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.39
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
TSHR P16473 1/20 0.36
CA1 P00915 1/20 0.35
BBOX1 O75936 3/20 0.33
CA4 P22748 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CA2 P00918 1/20 0.31
CASP1 P29466 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL11582867 0.94
SCHEMBL9435257 0.94
SCHEMBL11546181 0.90 FFAR3 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL18207954 0.90 FFAR3 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL11823085 0.85 FFAR3 (0.33) FFAR3HDAC3HDAC1HDAC2HDAC8
Zinc Ion SCHEMBL964589 0.79 TDP1 (0.42) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL11510626 0.79 CA1 (0.39) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL31230206 0.76 CA4 (0.47) FFAR3HDAC3HDAC1HDAC2HDAC8
Lithium Ion SCHEMBL31197165 0.76 CYP2D6 (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
Zinc Ion SCHEMBL965729 0.75 CES1 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed
EP-0987295-B1 Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing MORTON INT INC (US) 2004-07-21 EP disclosed
US-6462116-B2 POLYVINYL CHLORIDE(PVC), OR OTHER HALOPOLYMERS; 2-MERCAPTOETHANOL AND ZINC BIS(2-ETHYLHEXYLTHIOGLYCOLATE) FOR EXAMPLE; ELIMINATES ZINC BURN DURING PROCESSING MORTON INTERNATIONAL, INC. 2002-10-08 US disclosed
US-20010036987-A1 Combination of an organothio compound and a zinc mercapto ester as a heat stabilizer in PVC processing MORTON INTERNATIONAL, INC. 2001-11-01 US disclosed
EP-0987295-A1 Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing MORTON INTERNATIONAL, INC. (US) 2000-03-22 EP disclosed