SCHEMBL9644258

SCHEMBL9644258

CCCC1CCC(C)C1=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SENP8 Q96LD8 1/20 0.32
NLRP3 Q96P20 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
PIK3CD O00329 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511494 0.85 NPC1 (0.35) NPC1CASP3RAB9ASENP8NLRP3
SCHEMBL9644994 0.85 CYP1A2 (0.41)
SCHEMBL8468449 0.81
SCHEMBL18438883 0.79 NPC1 (0.33) NPC1CASP3RAB9ASENP8NLRP3
SCHEMBL10708390 0.75 CYP1A2 (0.38)
SCHEMBL6327304 0.71 CYP1A2 (0.41)
SCHEMBL14007681 0.71
SCHEMBL2344673 0.71
SCHEMBL18588306 0.71
SCHEMBL6332614 0.70 CYP1A2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5133903-A Process for the preparation of ω-enecarboxylic acid esters HUELS AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
EP-0401491-A2 Mixture of isomers of alkyl-methyl-tetrahydropyran-2-ones and a process for their preparation and use HÜLS AKTIENGESELLSCHAFT (DE) 1990-12-12 EP disclosed
EP-0366908-A1 Process for the preparation of 2-methyl-5-n-alkyl cyclo-pentanones HÜLS AKTIENGESELLSCHAFT (DE) 1990-05-09 EP disclosed
EP-0337083-A2 Process for the preparation of esters of omega enoic acids HÜLS AKTIENGESELLSCHAFT (DE) 1989-10-18 EP disclosed