Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.57 |
| ▸ | IGF1R | P08069 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945340 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL9845813 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL10411345 | 0.94 | NPC1 (0.55) | KAT8IGF1RALOX15PTGS2ESR1 | |
| Methoxymethane SCHEMBL6847722 | 0.93 | KAT8 (0.55) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL69580 | 0.82 | IGF1R (0.79) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL11616856 | 0.81 | IGF1R (0.76) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL11721061 | 0.81 | IGF1R (0.76) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL9447274 | 0.81 | IGF1R (0.76) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL68207 | 0.81 | IGF1R (0.76) | KAT8IGF1RALOX15PTGS2ESR1 | |
| SCHEMBL70343 | 0.81 | IGF1R (0.76) | KAT8IGF1RALOX15PTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5113019-A | PROCESS FOR PHENOL ALKYLTHIOLATION AND ITS APPLICATION TO THE SYNTHESIS OF 4-ACYL-2-ALKYLTHIOPHENOLS | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1992-05-12 | — | — | US | disclosed |