Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645375 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TDP1CYP1A2SPHK2 | |
| SCHEMBL9645379 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TDP1CYP1A2SPHK2 | |
| SCHEMBL9646561 | 0.96 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9406757 | 0.96 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9406753 | 0.96 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9647278 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9647528 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9406506 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9406515 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1CYP1A2 | |
| SCHEMBL9647518 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102578-A | Electrooptics | HOFFMANN-LA ROCHE INC. (US) | 1992-04-07 | — | — | US | disclosed |