Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722986 | 0.84 | PTGS1 (0.51) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL7323204 | 0.84 | PTGS1 (0.51) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL22722992 | 0.84 | PTGS1 (0.51) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL11766801 | 0.84 | PTGS1 (0.47) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL10749840 | 0.78 | NR1H4 (0.46) | ALOX5PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL764935 | 0.77 | PTGS1 (0.46) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| Dimethylamine SCHEMBL3820590 | 0.76 | EPHX1 (0.46) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL30619574 | 0.76 | PTGS1 (0.50) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL24473432 | 0.75 | PTGS1 (0.47) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL27901537 | 0.75 | TSHR (0.51) | EPHX1ALOX5PTGS1PTGS2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57093923-A | — | — | None | — | — | JP | disclosed |
| JP-52151144-A | — | — | None | — | — | JP | disclosed |
| WO-2016069952-A1 | ANTI-ACNE COMPOSITION AND METHODS OF USE | RAYUDU SREEDHAR RAO (US) | 2016-05-06 | — | — | WO | disclosed |
| US-5166434-A | Process for the preparation of aromatic-substituted unsaturated amides | ETHYL CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| JP-S5793923-A | PREPARATION OF 2-(4-ISOBUTYLPHENYL) PROPIONIC ACID | MITSUI TOATSU CHEM INC | 1982-06-11 | — | — | JP | disclosed |
| JP-S52151144-A | PREPARATION OF 2-SUBSTITUTED-ACRYLIC AMIDE AND 2-SUBSTITUTED-PROPIONIC ACID DERIVATIVES | MITSUI TOATSU CHEM INC | 1977-12-15 | — | — | JP | disclosed |