Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666282 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9664671 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9665849 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9665763 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9645746 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9665921 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9666943 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9666364 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL9666740 | 1.00 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2AESR1ADRA2A | |
| SCHEMBL7204684 | 0.88 | KCNH2 (0.71) | KCNH2SIGMAR1HTR2AESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507223-A1 | Phenyltrialkylsilane lubricating compositions | ETHYL CORPORATION (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5124502-A | Reacting sodium trialkylaluminum and phenyltrihalosilanes, controlling temperature | ETHYL CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-5120458-A | Hydraulic fluids, oxidation resistance | ETHYL CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |