Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037421 | 0.86 | KDM4E (0.49) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL21705368 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL12449350 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL12449338 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL111203 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL23187788 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL21706015 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL21706014 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| SCHEMBL22958632 | 0.82 | CYP19A1 (0.52) | EPHX1CYP19A1ALDH1A1HPGDMAPT | |
| Demannose SCHEMBL9474820 | 0.81 | EPHX1 (0.44) | EPHX1CYP19A1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139034-A | Mixture of tobacco filler and menthyloxy carbonylglucose compounds | PHILIP MORRIS INCORPORATED (US) | 1992-08-18 | — | — | US | claimed |
| EP-0486212-A2 | Smoking compositions containing a menthol-release additive | Philip Morris Products Inc. (US) | 1992-05-20 | — | — | EP | claimed |
| US-5139034-A | Mixture of tobacco filler and menthyloxy carbonylglucose compounds | PHILIP MORRIS INCORPORATED (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0486212-A2 | Smoking compositions containing a menthol-release additive | Philip Morris Products Inc. (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0486212-A2 | Smoking compositions containing a menthol-release additive | Philip Morris Products Inc. (US) | 1992-05-20 | — | — | EP | disclosed |