Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959497 | 0.84 | GBA1 (0.51) | GAAMAPTADORA1TSHRKMT2A | |
| SCHEMBL9645145 | 0.83 | GAA (0.55) | GAAMAPTADORA1TSHRKMT2A | |
| SCHEMBL22067845 | 0.79 | GBA1 (0.48) | GAAMAPTADORA1TSHRKMT2A | |
| SCHEMBL30433848 | 0.76 | CXCR2 (0.56) | GAAMAPTADORA1KMT2AMEN1 | |
| SCHEMBL3296650 | 0.76 | BRAF (0.50) | GAAMAPTADORA1TSHRKMT2A | |
| SCHEMBL9647957 | 0.75 | MAPK8 (0.59) | GAAMAPTADORA1KMT2AMEN1 | |
| SCHEMBL304891 | 0.72 | CXCR2 (0.54) | GAAMAPTKMT2AMEN1KDM4E | |
| Dyrene SCHEMBL21854003 | 0.71 | TSHR (0.83) | GAAMAPTADORA1TSHRKMT2A | |
| SCHEMBL16698318 | 0.70 | MAPT (0.49) | GAAMAPTADORA1KMT2AMEN1 | |
| SCHEMBL10358476 | 0.70 | GBA1 (0.73) | GBA1VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372623-A2 | Flame-resistant polycarbonates containing units deriving from halogenated pyrimidine compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-13 | — | — | EP | claimed |
| US-5166306-A | Self-extinguishing polycarbonates | ENICHEM TECHNORESINE S.P.A. (IT) | 1992-11-24 | — | — | US | disclosed |
| US-5098989-A | Copolymers that are self-extinguishing formed by reaction of carbonate precursor, a dihydroxyaromatic compound and a halogenated pyrimidine and a branching compound | ENICHEM TECNORESINE S.P.A. (IT) | 1992-03-24 | — | — | US | disclosed |
| EP-0372623-A2 | Flame-resistant polycarbonates containing units deriving from halogenated pyrimidine compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |