Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646947 | 0.83 | CA1 (0.42) | POLBMEN1KMT2ASENP7LMNA | |
| SCHEMBL9646039 | 0.80 | SLC7A11 (0.36) | POLBMEN1KMT2ASENP7SUMO2 | |
| SCHEMBL1755154 | 0.78 | BRD4 (0.49) | POLBMEN1KMT2ASENP7SUMO2 | |
| SCHEMBL9646033 | 0.77 | MEN1 (0.38) | POLBMEN1KMT2ASENP7SUMO2 | |
| SCHEMBL6913682 | 0.74 | CA1 (0.47) | POLBMEN1KMT2ASENP7ESR1 | |
| SCHEMBL11518496 | 0.73 | MEN1 (0.59) | POLBMEN1KMT2ASENP7ESR1 | |
| SCHEMBL9510321 | 0.72 | TDP1 (0.46) | LMNAAPEX1L3MBTL1CA1CA2 | |
| SCHEMBL8989782 | 0.72 | CA1 (0.46) | POLBMEN1KMT2ASENP7LMNA | |
| SCHEMBL6938187 | 0.72 | CYP3A4 (0.44) | POLBMEN1KMT2ASENP7SUMO2 | |
| SCHEMBL8069286 | 0.71 | CYP3A4 (0.44) | POLBMEN1KMT2ASENP7SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0039306-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-01-11 | — | — | EP | disclosed |
| EP-0039306-A1 | Azo dyestuffs, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |