Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100244 | 0.80 | — | — | |
| SCHEMBL1073565 | 0.67 | — | — | |
| SCHEMBL7029411 | 0.67 | — | — | |
| SCHEMBL17874213 | 0.67 | — | — | |
| SCHEMBL12595244 | 0.64 | — | — | |
| SCHEMBL19285856 | 0.64 | — | — | |
| SCHEMBL14208341 | 0.63 | — | — | |
| SCHEMBL8632258 | 0.63 | — | — | |
| SCHEMBL13597724 | 0.63 | SMN1; SMN2 (0.32) | CRBNSMN1; SMN2 | |
| SCHEMBL351712 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286315-B1 | BIS-(1,2,3-TRIAZOL-1-YL)DERIVATIVES | AUSIMONT S.p.A. (IT) | 1992-11-19 | — | — | EP | claimed |
| US-4916232-A | Bis-(1,2,3-triazol-1-yl)-derivatives | AUSIMONT S.P.A. (IT) | 1990-04-10 | — | — | US | claimed |
| EP-0286315-A1 | Bis-(1,2,3-triazol-1-yl)derivatives | AUSIMONT S.p.A. (IT) | 1988-10-12 | — | — | EP | claimed |
| EP-2217452-B1 | TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING DIAZIDE CROSSLINKING AGENTS | PIRELLI (IT) | 2011-04-20 | — | — | EP | disclosed |
| WO-2009071122-A1 | TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING DIAZIDE CROSSLINKING AGENTS | PIRELLI TYRE S.P.A. (IT) | 2009-06-11 | — | — | WO | disclosed |