Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 5/20 | 0.38 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649156 | 1.00 | HRH3 (0.42) | HRH3KCNH2TSHRHSD17B10HRH2 | |
| SCHEMBL9648588 | 0.96 | GRIA1 (0.40) | HRH3KCNH2TSHRGRIA2GRIA1 | |
| SCHEMBL9648597 | 0.96 | GRIA1 (0.40) | HRH3KCNH2TSHRGRIA2GRIA1 | |
| SCHEMBL9649561 | 0.88 | GRIA1 (0.39) | HRH3KCNH2GRIA2GRIA1GRIA3 | |
| SCHEMBL9649553 | 0.88 | GRIA1 (0.39) | HRH3KCNH2GRIA2GRIA1GRIA3 | |
| SCHEMBL9648244 | 0.87 | GRIA1 (0.38) | HRH3KCNH2TSHRHSD17B10GRIA2 | |
| SCHEMBL9648239 | 0.87 | GRIA1 (0.38) | HRH3KCNH2TSHRHSD17B10GRIA2 | |
| SCHEMBL9649306 | 0.86 | TSHR (0.39) | HRH3KCNH2TSHRHSD17B10GRIA2 | |
| SCHEMBL9649297 | 0.86 | TSHR (0.39) | HRH3KCNH2TSHRHSD17B10GRIA2 | |
| SCHEMBL9648242 | 0.85 | TSHR (0.41) | TSHRHSD17B10GRIA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108652-A | Liquid crystal dielectrics | Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) | 1992-04-28 | — | — | US | disclosed |
| US-4510069-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-09 | — | — | US | disclosed |