Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527905 | 0.90 | USP2 (0.44) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL20041604 | 0.88 | HSD17B10 (0.41) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL7204254 | 0.88 | HSD17B10 (0.41) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL19151386 | 0.84 | USP2 (0.58) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL24615028 | 0.84 | USP2 (0.58) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL13108262 | 0.83 | USP2 (0.54) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL13108265 | 0.83 | USP2 (0.59) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL12833042 | 0.79 | USP2 (0.47) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL2609781 | 0.79 | USP2 (0.61) | USP2HTTSPHK1HSD17B10LPAR5 | |
| SCHEMBL9731460 | 0.79 | USP2 (0.61) | USP2HTTSPHK1HSD17B10LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071809-A | TERTIARY AMINE CATALYSTS FOR POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-12-10 | — | — | US | claimed |
| EP-0456194-A2 | Tertiary amine catalysts for polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-13 | — | — | EP | claimed |
| US-5091583-A | Also provides extended pot life | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5071809-A | TERTIARY AMINE CATALYSTS FOR POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0456194-A2 | Tertiary amine catalysts for polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-13 | — | — | EP | disclosed |