Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650178 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9648739 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9650173 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9650011 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9650414 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9650007 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9648727 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9646587 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9646591 | 1.00 | RARB (0.43) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9649663 | 0.99 | RARB (0.41) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167858-A | Pyrimidine derivative and liquid crystal composition contain the same | CHISSO CORPORATION (JP) | 1992-12-01 | — | — | US | disclosed |