⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131097 | 1.00 | — | — | |
| SCHEMBL13637530 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27397572 | 0.98 | — | — | |
| Trimethylammonium SCHEMBL28039770 | 0.92 | — | — | |
| Dimethylamine SCHEMBL27638727 | 0.92 | — | — | |
| SCHEMBL27494311 | 0.86 | — | — | |
| SCHEMBL29197949 | 0.79 | — | — | |
| SCHEMBL293363 | 0.76 | — | — | |
| SCHEMBL18531888 | 0.76 | — | — | |
| SCHEMBL159078 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483164-B1 | PYRROLOPYRROLE COMPOSITIONS AS PYRUVATE KINASE (PKR) ACTIVATORS | FORMA THERAPEUTICS INC (US) | 2020-03-04 | — | — | EP | claimed |
| CN-106008491-B | A kind of preparation method of razaxaban | 苏州汇和药业有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-109111435-A | A kind of pyrrolidines sulfonyl-derivatives ROR gamma modulators and application thereof | 南京柯菲平盛辉制药有限公司 | 2019-01-01 | — | — | CN | claimed |
| CN-109111418-A | A kind of 2,3- dihydro -1H- indenes -4- sulfonamide ROR gamma modulators and application thereof | 南京柯菲平盛辉制药有限公司 | 2019-01-01 | — | — | CN | claimed |
| CN-108884029-A | L SD1 inhibitors | 米拉蒂医疗股份有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108690010-A | The preparation process of razaxaban | 苏州中联化学制药有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-108290846-A | Acylated N- (1,2,5- oxadiazole -3- bases) -, N- (1,3,4- oxadiazole -2- bases) -, N- (tetrazolium -5- bases)-and N- (triazole -5- bases)-aryl carboxylic acid amides and its purposes as herbicide | 拜耳作物科学股份公司 | 2018-07-17 | — | — | CN | claimed |
| CN-108250193-A | The method that one kettle way prepares razaxaban | 江苏中邦制药有限公司 | 2018-07-06 | — | — | CN | claimed |
| CN-108218845-A | A kind of chroman -6- sulfonamide ROR gamma modulators and application thereof | 南京柯菲平盛辉制药有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-108164519-A | The synthetic method of razaxaban process contaminants | 江苏悦兴医药技术有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-104487436-B | Improved process for preparing rivaroxaban using intermediates | 信谊实验室有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106661049-A | Substituted tetrahydropyridothienopyrimidines | 拜耳制药股份公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104447607-B | preparation method of Aprepitant intermediate | 瑞阳制药有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-101981035-A | Triazolium salts as PAR1 inhibitors, their preparation and their use as medicaments | SANOFI AVENTIS | 2011-02-23 | — | — | CN | claimed |
| US-7867992-B2 | such as 1-Cyclopropyl-N-(2,4-dichlorobenzyl)-6-fluoro-8-methoxy-7-[3-methyl-4-(2-{[(methylamino)carbonyl]amino}-2-oxoethyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxamide, used for the treatment and/or prophylaxis of viral diseases or infections, particularly against cytomegaloviruses | AICURIS GMBH & CO. KG (DE) | 2011-01-11 | — | — | US | claimed |
| US-20070293478-A1 | Substituted quinolones | BAYER HEALTHCARE AG (DE) | 2007-12-20 | — | — | US | claimed |
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | claimed |
| CN-1968922-A | Factor XA inhibitors | MILLENNIUM PHARM INC (US) | 2007-05-23 | — | — | CN | claimed |
| EP-1768973-A1 | SUBSTITUTED QUINOLONES | AiCuris GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006008046-A1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO. KG (DE) | 2006-01-26 | — | — | WO | claimed |