Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 11/20 | 0.58 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075872 | 0.79 | KMT2A (0.67) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL4579357 | 0.78 | KMT2A (0.66) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL13241602 | 0.74 | KMT2A (0.46) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL3425042 | 0.74 | KMT2A (1.00) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL3425040 | 0.74 | KMT2A (1.00) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL3423456 | 0.71 | KMT2A (0.71) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL10701274 | 0.69 | MEN1 (0.50) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL25573 | 0.68 | GSK3A (0.47) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL28332104 | 0.68 | KMT2A (0.65) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL3423470 | 0.68 | KMT2A (0.65) | KMT2AMEN1GSK3AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108887-A | Zeromethine merocyanine dyes as J-aggregating spectral sensitizers for tabular emulsions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| US-4110116-A | Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-08-29 | — | — | US | disclosed |