Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250771 | 1.00 | KDM4E (0.51) | KDM4ENPSR1CYP3A4THRBTSHR | |
| SCHEMBL3250767 | 1.00 | KDM4E (0.51) | KDM4ENPSR1CYP3A4THRBTSHR | |
| SCHEMBL3250768 | 1.00 | KDM4E (0.51) | KDM4ENPSR1CYP3A4THRBTSHR | |
| SCHEMBL9652237 | 1.00 | KDM4E (0.51) | KDM4ENPSR1CYP3A4THRBTSHR | |
| Hydrochloric Acid SCHEMBL29358906 | 0.98 | KDM4E (0.50) | KDM4ENPSR1CYP3A4THRBTSHR | |
| Hydrochloric Acid SCHEMBL1793245 | 0.98 | KDM4E (0.50) | KDM4ENPSR1CYP3A4THRBTSHR | |
| Hydrochloric Acid SCHEMBL1793249 | 0.98 | KDM4E (0.50) | KDM4ENPSR1CYP3A4THRBTSHR | |
| Hydrochloric Acid SCHEMBL1793247 | 0.98 | KDM4E (0.50) | KDM4ENPSR1CYP3A4THRBTSHR | |
| SCHEMBL11059909 | 0.82 | CYP3A4 (0.43) | KDM4ENPSR1CYP3A4THRBTSHR | |
| SCHEMBL9652192 | 0.81 | MAPT (0.45) | KDM4ENPSR1CYP3A4THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292305-B1 | NOVEL THIAZOLIDIN-4-ONE DERIVATIVES AND ACID ADDITION SALTS THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5106860-A | Treating inflammation, circulatory disease, gastrointestinal ulceration, allergies | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021435-A | Administering to a patient suffering from an ulcer caused by stress or gastric acid | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4992455-A | Cardiovascular disorders | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0325496-A1 | 2-Pyridyl thiazolidin-4-one derivatives as anti-ulcer agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0292305-A1 | Novel thiazolidin-4-one derivatives and acid addition salts thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-23 | — | — | EP | disclosed |