Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975014 | 0.81 | EEF2K (0.48) | EEF2KPLK1PLK2PTPN1HIF1A | |
| SCHEMBL18992936 | 0.80 | EEF2K (0.52) | EEF2KPLK1PLK2PTPN1HIF1A | |
| SCHEMBL17499950 | 0.75 | EEF2K (0.47) | EEF2KPLK1PLK2PTPN1HIF1A | |
| SCHEMBL9653457 | 0.73 | MAPT (0.41) | EEF2KPLK1PLK2HIF1ACDC25A | |
| SCHEMBL9654631 | 0.73 | AURKA (0.34) | HIF1AMAPK1MEN1GAAKMT2A | |
| SCHEMBL9655526 | 0.70 | PTPRC (0.34) | — | |
| SCHEMBL11602759 | 0.69 | PLK1 (0.75) | EEF2KPLK1PLK2PTPN1HIF1A | |
| SCHEMBL5587282 | 0.68 | CDC25A (0.41) | EEF2KPLK1PLK2PTPN1CDC25A | |
| SCHEMBL5590497 | 0.68 | CDC25A (0.41) | EEF2KPLK1PLK2PTPN1CDC25A | |
| SCHEMBL28802328 | 0.68 | CA12 (0.38) | EEF2KPLK1PLK2PTPN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355492-B1 | REACTIVE DYES | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5138054-A | Colorfastness, photostability; red dye | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0255020-B1 | WATER SOLUBLE TRIPHENODIOXAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |
| EP-0229339-B1 | WATER SOLUBLE TRIPHENE DIOXAZINE COMPOUNDS, THEIR STARTING COMPOUNDS CONTAINING SULPHONYL GROUPS, PROCESS FOR THEIR PREPARATION AND USE OF THE TRIPHENE DIOXAZINES AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0355492-A1 | Reactive dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4898944-A | Precursors for the preparation of water-soluble triphendioxazine dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |
| US-4895954-A | Dyeing wool, cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| US-4816574-A | FIBER-REACTIVE DYES FOR WOOL, CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |
| US-4786728-A | FIBER-REACTIVE DYES FOR COTTON | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-22 | — | — | US | disclosed |
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0141996-B1 | TRIPHENDIOXAZINE REACTIVE DYES | BAYER AG (DE) | 1987-11-25 | — | — | EP | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |
| EP-0144580-B1 | TRIPHENDIOXAZINE DYES | BAYER AG (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0222098-A2 | Water soluble triphenodioxazine compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-20 | — | — | EP | disclosed |
| US-4629788-A | COLORFASTNESS; BLUE COLOR; NATURAL AND SYNTHETIC FIBER | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| US-4591643-A | Triphendioxazine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0144580-A2 | Triphendioxazine dyes | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| EP-0141996-A2 | Triphendioxazine reactive dyes | BAYER AG (DE) | 1985-05-22 | — | — | EP | disclosed |