Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656081 | 0.99 | HRH3 (0.51) | HRH3BCHEACHEALDH1A1TP53 | |
| SCHEMBL9599491 | 0.96 | HRH3 (0.54) | HRH3 | |
| Hydrochloric Acid SCHEMBL9600032 | 0.95 | HRH3 (0.53) | HRH3 | |
| Hydrochloric Acid SCHEMBL9599538 | 0.94 | HRH3 (0.50) | HRH3ALDH1A1TP53TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL9598375 | 0.94 | HRH3 (0.53) | HRH3ALDH1A1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL10337873 | 0.91 | HRH3 (0.50) | HRH3BCHEACHE | |
| Hydrochloric Acid SCHEMBL9656561 | 0.91 | HRH3 (0.48) | HRH3BCHEACHE | |
| SCHEMBL9656112 | 0.87 | HRH3 (0.48) | HRH3BCHEACHEALDH1A1TP53 | |
| Oxalic Acid SCHEMBL9599094 | 0.87 | HRH3 (0.48) | HRH3BCHEACHE | |
| Oxalic Acid SCHEMBL9598423 | 0.87 | HRH3 (0.48) | HRH3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5039700-A | Cardiovascular disorders, antitumor agents | SANOFI (FR) | 1991-08-13 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |