Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587166 | 1.00 | KMT2A (0.38) | KMT2ACA1CA2CA4GAA | |
| SCHEMBL6591267 | 0.98 | — | — | |
| Cyclohexane SCHEMBL8177759 | 0.93 | KMT2A (0.34) | KMT2ACA1CA2CA4 | |
| SCHEMBL791134 | 0.90 | — | — | |
| SCHEMBL717556 | 0.90 | — | — | |
| SCHEMBL715768 | 0.79 | — | — | |
| SCHEMBL6591357 | 0.79 | KMT2A (0.37) | KMT2ACA1CA2CA4 | |
| SCHEMBL6593183 | 0.76 | — | — | |
| SCHEMBL6587162 | 0.74 | — | — | |
| SCHEMBL21477509 | 0.73 | KMT2A (0.35) | KMT2ACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145562-A | Pyrrolidone derivatives | PHILLIPS PETROLEUM COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-5135617-A | N-/b-hydroxyethyl/-2-pyrrolidone and/or cyclohexanol as solvent | PHILLIPS PETROLEUM COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4233230-A | Process for preparing olefins by metathesis of cyclic olefins with acyclic olefins | RHONE-POULENC INDUSTRIES (FR) | 1980-11-11 | — | — | US | disclosed |