Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefmenoxime. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 1.00 |
| ▸ | PGR | P06401 | 3/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.77 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.77 |
| ▸ | DAO | P14920 | 1/20 | 0.77 |
| ▸ | SNCA | P37840 | 1/20 | 0.77 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.76 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.69 |
| ▸ | APEX1 | P27695 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefmenoxime SCHEMBL10492384 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL1813696 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL3252593 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL32668883 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL10492342 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL152861 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL16072811 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL10633730 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL8768620 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL8517340 | 1.00 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53068796-A | — | — | None | — | — | JP | disclosed |
| US-5079369-A | N-acylating agent | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| US-4877873-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4871860-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-caroxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4804752-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-14 | — | — | US | disclosed |
| US-4544653-A | BACTERICIDAL CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4493833-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4431643-A | CEPHALOSPORINS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-14 | — | — | US | disclosed |
| US-4364943-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |
| US-4331664-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4316019-A | AMIDATION BY A 2-ALKOXYIMINO-2-THIAZOLYLACETIC ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| US-4304770-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-4279818-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4166115-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| JP-S5368796-A | SYN-ISOMER OF 3,7-DISUBSTD.-3-CEPHEM-4-CARBOXYLIC ACIDS, AND THEIR PREVENTINGOR TREATING AGENTS CONTAINING THEIR SALTS AS ACTIVE CONSTITUENT AGAINSTDISEASES CAUSED BY BACTERIAL INFECTION | FUJISAWA PHARMACEUT CO LTD | 1978-06-19 | — | — | JP | disclosed |