Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12186391 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL1257711 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3ADRA2A | |
| SCHEMBL15159757 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL15154702 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL12186424 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL12186434 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL15154765 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL2599626 | 0.86 | TSHR (0.43) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL19493871 | 0.81 | SLC6A2 (0.45) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL2061940 | 0.78 | CHRNB4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| EP-0403885-A1 | Utilization of 3-hydroxybenzothiophens for combatting endoparasites, new 3-hydroxythiophens and process for their preparation | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |