Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842604 | 0.90 | KMT2A (0.60) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL10704632 | 0.89 | KMT2A (0.65) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL27290860 | 0.88 | KMT2A (0.64) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL9200117 | 0.88 | CYP3A4 (0.58) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL9792768 | 0.88 | KMT2A (0.57) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL17325283 | 0.87 | HSP90AA1 (0.50) | CYP3A4ALDH1A1KMT2AHSP90AA1CYP2C9 | |
| SCHEMBL15832956 | 0.86 | HSP90AA1 (0.49) | CYP3A4ALDH1A1KMT2AHSP90AA1CYP2C9 | |
| SCHEMBL17309019 | 0.86 | HSP90AA1 (0.49) | CYP3A4ALDH1A1KMT2AHSP90AA1CYP2C9 | |
| SCHEMBL10557832 | 0.85 | KMT2A (0.55) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT | |
| SCHEMBL9573811 | 0.85 | KMT2A (0.55) | CYP3A4ALDH1A1KMT2AHSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047594-A2 | Triazole compounds, a process for preparing them, their use as plant fungicides and plant growth regulators and compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-17 | — | — | EP | claimed |
| EP-0123160-B1 | TRIAZOLE COMPOUNDS, A PROCESS FOR PREPARING THEM, THEIR USE AS PLANT FUNGICIDES AND PLANT GROWTH REGULATORS AND COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1992-10-28 | — | — | EP | disclosed |
| EP-0131684-B1 | USE OF TRIAZOLYLETHANOL DERIVATIVES AND THEIR COMPOSITIONS AS NON-AGRICULTURAL FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| US-4880457-A | FUNGICIDES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-14 | — | — | US | disclosed |
| EP-0131684-A2 | Use of triazolylethanol derivatives and their compositions as non-agricultural fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-23 | — | — | EP | disclosed |
| EP-0123160-A2 | Triazole compounds, a process for preparing them, their use as plant fungicides and plant growth regulators and compositions containing them | ZENECA LIMITED (GB) | 1984-10-31 | — | — | EP | disclosed |
| EP-0047594-A2 | Triazole compounds, a process for preparing them, their use as plant fungicides and plant growth regulators and compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-17 | — | — | EP | disclosed |