Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662765 | 1.00 | MAPT (0.48) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10793763 | 0.95 | NR1I2 (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10875502 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9668395 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL11078983 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9661346 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9661349 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10793761 | 0.95 | NR1I2 (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9666794 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9666798 | 0.95 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143911-A | Bactericides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0475150-A1 | Antibiotic C-3 di-hydroxyphenyl substituted cephalosporin compounds, compositions and use thereof | Bristol-Myers Squibb Company (US) | 1992-03-18 | — | — | EP | disclosed |