Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | FAP | Q12884 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662949 | 1.00 | NR1I2 (0.53) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL9662288 | 0.93 | MAPT (0.46) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL9662294 | 0.93 | MAPT (0.46) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL10793836 | 0.91 | NR1I2 (0.62) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL10792786 | 0.91 | NR1I2 (0.62) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL10792780 | 0.91 | NR1I2 (0.62) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL10793834 | 0.91 | NR1I2 (0.62) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL9661415 | 0.90 | MAPT (0.41) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL9661408 | 0.90 | MAPT (0.41) | NR1I2MAPTALBPPARGSLC22A6 | |
| SCHEMBL10793269 | 0.86 | NR1I2 (0.60) | NR1I2MAPTALBPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143911-A | Bactericides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0475150-A1 | Antibiotic C-3 di-hydroxyphenyl substituted cephalosporin compounds, compositions and use thereof | Bristol-Myers Squibb Company (US) | 1992-03-18 | — | — | EP | disclosed |