Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698144 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19 | |
| SCHEMBL1698141 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19 | |
| SCHEMBL1698146 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19 | |
| SCHEMBL11393510 | 0.80 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL1141590 | 0.77 | CYP2D6 (0.41) | CYP2D6CYP2C19 | |
| SCHEMBL13320133 | 0.77 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL11736269 | 0.73 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL11613246 | 0.73 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL3110268 | 0.72 | CYP2D6 (0.42) | CYP2D6CYP2C19 | |
| SCHEMBL31695302 | 0.69 | CYP2D6 (0.34) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281121-B1 | 1-(1-ARYL-2-HYDROXY-ETHYL)-IMIDAZOLES AND THEIR SALTS, PROCESSES FOR THEIR PREPARATION, DRUGS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4999352-A | Antidepressants or fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0281121-A1 | 1-(1-Aryl-2-hydroxy-ethyl)-imidazoles and their salts, processes for their preparation, drugs containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |