Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664957 | 0.99 | RARB (0.55) | RARBRARARARGCASP3SENP8 | |
| SCHEMBL9664333 | 0.90 | MAOB (0.53) | RARBRARARARGMAOBESR1 | |
| SCHEMBL9663861 | 0.89 | RARB (0.58) | RARBRARARARGESR1PTGS2 | |
| SCHEMBL9662872 | 0.87 | MAOB (0.53) | MAOBESR1CYP19A1ESR2CALM1 | |
| SCHEMBL9664990 | 0.87 | RARB (0.60) | RARBRARARARGESR1PTGS2 | |
| SCHEMBL9399298 | 0.87 | RARB (0.62) | RARBRARARARGESR1ALOX15 | |
| SCHEMBL9399744 | 0.87 | RARB (0.62) | RARBRARARARGESR1ALOX15 | |
| SCHEMBL17614877 | 0.86 | RARB (0.56) | RARBRARARARGCASP3SENP8 | |
| SCHEMBL19722309 | 0.86 | RARB (0.56) | RARBRARARARGCASP3SENP8 | |
| SCHEMBL9400064 | 0.86 | RARB (0.61) | RARBRARARARGESR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093026-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-03 | — | — | US | disclosed |
| WO-1990008756-A1 | DIPHENYLETHANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |