Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943630 | 0.98 | RARB (0.49) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL9665285 | 0.98 | RARB (0.49) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL10943636 | 0.98 | RARB (0.49) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL10945641 | 0.97 | RARB (0.50) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL10945649 | 0.97 | RARB (0.50) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL9662921 | 0.95 | RARB (0.44) | RARBSPHK1SPHK2FFAR4CYP3A4 | |
| SCHEMBL9663379 | 0.95 | RARB (0.49) | RARBSPHK1SPHK2FFAR4RARA | |
| SCHEMBL10947684 | 0.95 | RARB (0.46) | RARBSPHK1SPHK2FFAR4CYP3A4 | |
| SCHEMBL10947677 | 0.95 | RARB (0.46) | RARBSPHK1SPHK2FFAR4CYP3A4 | |
| SCHEMBL9665276 | 0.94 | RARB (0.43) | RARBSPHK1SPHK2FFAR4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093026-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-03 | — | — | US | disclosed |
| WO-1990008756-A1 | DIPHENYLETHANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |