Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nerispirdine SCHEMBL29379158 | 0.83 | SLC6A2 (0.67) | SLC6A2BCHECYP2D6 | |
| Nerispirdine SCHEMBL3842518 | 0.83 | SLC6A2 (0.67) | SLC6A2BCHECYP2D6 | |
| Nerispirdine SCHEMBL3855895 | 0.82 | SLC6A2 (0.65) | SLC6A2BCHECYP2D6 | |
| SCHEMBL7610193 | 0.81 | SLC6A2 (0.66) | SLC6A2BCHE | |
| SCHEMBL7611649 | 0.80 | SLC6A2 (0.65) | SLC6A2BCHE | |
| SCHEMBL7609242 | 0.79 | BCHE (0.42) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL3977692 | 0.79 | SLC6A2 (0.64) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL7643682 | 0.78 | BCHE (0.41) | SLC6A2BCHE | |
| SCHEMBL9663535 | 0.77 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL10402598 | 0.75 | SLC6A2 (0.57) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868190-A | ANALGESICS, ALZHEIMER*S DISEASE, ANTICONVULSANTS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-09-19 | — | — | US | claimed |
| EP-0376155-B1 | N-PYRIDINYL-9H-CARBAZOL-9-AMINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0376155-A1 | N-Pyridinyl-9H-carbazol-9-amines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4868190-A | ANALGESICS, ALZHEIMER*S DISEASE, ANTICONVULSANTS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-09-19 | — | — | US | disclosed |