Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839631 | 0.79 | KMT2A (0.63) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL31141860 | 0.79 | TDP1 (0.52) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL1403191 | 0.79 | TDP1 (0.52) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL2463525 | 0.78 | TDP1 (0.55) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL30226651 | 0.75 | KMT2A (0.61) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL3038674 | 0.75 | TSHR (0.41) | TDP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL2784281 | 0.75 | TSHR (0.41) | TDP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14108352 | 0.75 | CYP1A2 (0.48) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL28349081 | 0.75 | TDP1 (0.47) | TDP1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL21881869 | 0.74 | KMT2A (0.66) | TDP1MAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341754-B1 | USE OF CARBAMATE OR THIOCARBAMATE DERIVATIVES FOR TREATMENT OF FUNGAL INFECTIONS | Tosoh Corporation (JP) | 1992-12-09 | — | — | EP | disclosed |