Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667744 | 1.00 | TDP1 (0.38) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL9668088 | 1.00 | TDP1 (0.38) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL9666735 | 1.00 | TDP1 (0.38) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL9668279 | 0.99 | TDP1 (0.39) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL28266138 | 0.92 | TDP1 (0.34) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL9862980 | 0.91 | TDP1 (0.38) | TDP1SCARB1NPC1RAB9AMAPT | |
| SCHEMBL9667787 | 0.90 | SCARB1 (0.39) | SCARB1KCNH2HRH3MEN1KMT2A | |
| SCHEMBL9705703 | 0.90 | SCARB1 (0.39) | SCARB1KCNH2HRH3MEN1KMT2A | |
| SCHEMBL9863055 | 0.88 | SCARB1 (0.36) | TDP1SCARB1KCNH2HRH3MEN1 | |
| SCHEMBL9862948 | 0.88 | SCARB1 (0.36) | SCARB1MAPTKCNH2HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137242-B1 | (SUBSTITUTED) PHENYL-ALIPHATIC-ISOXAZOLES USEFUL AS ANTIVIRAL AGENTS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-05-13 | — | — | EP | claimed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | claimed |
| EP-0137242-A2 | (Substituted) Phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof | STERLING WINTHROP INC. (US) | 1985-04-17 | — | — | EP | claimed |
| EP-0137242-B1 | (SUBSTITUTED) PHENYL-ALIPHATIC-ISOXAZOLES USEFUL AS ANTIVIRAL AGENTS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0137242-A2 | (Substituted) Phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof | STERLING WINTHROP INC. (US) | 1985-04-17 | — | — | EP | disclosed |