Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2745120 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL9508243 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL5057971 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL739382 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL2745290 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL741426 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL738622 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL739572 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL2744960 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL2745110 | 0.86 | NR5A1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510473-A1 | Thienyl-nonatetraenoic acid derivatives with anti-rheumatic activity | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-28 | — | — | EP | disclosed |