SCHEMBL9668385

SCHEMBL9668385

CC1(C)CC(NC(=O)CCN)CC(C)(C)N1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.63
HTT P42858 2/20 0.55
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.54
USP2 O75604 1/20 0.50
POLB P06746 4/20 0.47
RECQL P46063 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
EZH2 Q15910 1/20 0.46
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2901212 0.89 GAA (0.71) GAAHTTKMT2AKDM4EUSP2
SCHEMBL1647940 0.86 GAA (0.67) GAAHTTKMT2AKDM4EUSP2
SCHEMBL10079252 0.86 GAA (0.58) GAAHTTKMT2AKDM4EUSP2
SCHEMBL7766498 0.85 GAA (0.61) GAAHTTKMT2AKDM4EUSP2
SCHEMBL8334264 0.85 GAA (0.61) GAAHTTKMT2AKDM4EUSP2
SCHEMBL4094277 0.84 GAA (0.65) GAAHTTKMT2AKDM4EUSP2
SCHEMBL9456922 0.84 GAA (0.65) GAAHTTKMT2AKDM4EUSP2
SCHEMBL8088104 0.83 GAA (0.60) GAAHTTKMT2AKDM4EUSP2
SCHEMBL10559499 0.83 GAA (0.63) GAAHTTKMT2AKDM4EUSP2
SCHEMBL9002854 0.82 GAA (0.58) GAAHTTKMT2AKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0358016-B1 2,6-POLYALKYLPIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-2-CARBOXYLIC-ACID ANILIDES, AND THEIR USE IN THE STABILISATION OF ORGANIC MATERIAL BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-4940742-A 2,6-polyalkylpiperidine-substituted benzimidazole-2-carboxanilides and their use for stabilizing organic material BASF AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
EP-0358016-A1 2,6-Polyalkylpiperidine-substituted benzimidazole-2-carboxylic-acid anilides, and their use in the stabilisation of organic material BASF Aktiengesellschaft (DE) 1990-03-14 EP disclosed