Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260577 | 0.86 | CYP3A4 (0.72) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| Bromide SCHEMBL11260548 | 0.85 | CYP3A4 (0.71) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9669060 | 0.85 | CYP3A4 (0.74) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL11259603 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9669136 | 0.80 | CYP3A4 (0.55) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9669062 | 0.78 | CYP3A4 (0.72) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9669156 | 0.75 | CYP3A4 (0.67) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9669349 | 0.74 | SYK (0.47) | CTSKTACR1 | |
| SCHEMBL17512983 | 0.74 | CYP3A4 (0.74) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9667731 | 0.72 | CYP3A4 (0.75) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293351-B1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| US-4990534-A | Aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1991-02-05 | — | — | US | disclosed |
| EP-0362264-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988009327-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0293351-A2 | New aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1988-11-30 | — | — | EP | disclosed |