Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669369 | 0.89 | MAOB (0.53) | MAOB | |
| SCHEMBL9670173 | 0.83 | MAOB (0.40) | MAOB | |
| SCHEMBL9668860 | 0.82 | MAPT (0.48) | MAOB | |
| SCHEMBL10557051 | 0.81 | MAOB (0.44) | MAOB | |
| SCHEMBL9667436 | 0.80 | MAOB (0.49) | MAOB | |
| SCHEMBL9668891 | 0.79 | PDE3B (0.59) | — | |
| SCHEMBL9669186 | 0.78 | CDC7 (0.40) | — | |
| SCHEMBL9667675 | 0.78 | KCNH2 (0.52) | — | |
| SCHEMBL9667872 | 0.74 | PDE3B (0.53) | — | |
| SCHEMBL31317792 | 0.74 | CLK1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4851406-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0223937-A1 | Indoles substituted with heterocycles, intermediates, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | disclosed |