Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446778 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL321523 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL600971 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL599897 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL600275 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL194341 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL601351 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL194585 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL321157 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 | |
| SCHEMBL320922 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511366-A1 | CHEMILUMINESCENT COMPOUNDS | BECKMAN INSTRUMENTS, INC. (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992009580-A1 | CHEMILUMINESCENT COMPOUNDS | BECKMAN INSTRUMENTS, INC. (US) | 1992-06-11 | — | — | WO | disclosed |