Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15352395 | 0.83 | UGT2B7 (0.54) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL27994700 | 0.81 | UGT2B7 (0.52) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL15352901 | 0.81 | UGT2B7 (0.52) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL132329 | 0.81 | UGT2B7 (0.63) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL30559658 | 0.80 | UGT2B7 (0.56) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL1538959 | 0.80 | UGT2B7 (0.56) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL11431877 | 0.80 | UGT2B7 (0.56) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL30559659 | 0.80 | UGT2B7 (0.56) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL2837489 | 0.79 | UGT2B7 (0.60) | UGT2B7CYP2A6MEN1KMT2AATM | |
| SCHEMBL9179436 | 0.77 | UGT2B7 (0.71) | UGT2B7CYP2A6MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | claimed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |