Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136022 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL27915750 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL29263622 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL28260636 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL29031284 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL7007425 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL29145044 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL28347622 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL28669182 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL11447322 | 0.98 | HRH1 (0.65) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863917-A | A kind of preparation method of 2,5- dimethoxy-pyridine | 穆云 | 2018-11-23 | — | — | CN | disclosed |
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4341906-A | ANALGESICS | PFIZER INC. (US) | 1982-07-27 | — | — | US | disclosed |
| US-4310669-A | TETRALONE | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310529-A | ANALGESICS | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310668-A | Intermediates to 1,9-dihydroxyoctahydrophenanthrenes | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4270005-A | ANALGESICS | PFIZER INC. (US) | 1981-05-26 | — | — | US | disclosed |
| US-4268523-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4268692-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4237133-A | ANALGESICS | PFIZER INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4188495-A | 1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |