Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672164 | 0.94 | ADORA2A (0.41) | ADORA2AADORA2BSLC29A1TP53GMNN | |
| SCHEMBL9671727 | 0.91 | ADORA2A (0.50) | ADORA2AADORA2BSLC29A1GMNNNFKB1 | |
| SCHEMBL9671559 | 0.88 | ADORA2A (0.48) | ADORA2AADORA2BSLC29A1TP53GMNN | |
| SCHEMBL9673598 | 0.88 | ADORA2A (0.47) | ADORA2AADORA2BSLC29A1GMNNNFKB1 | |
| SCHEMBL9671694 | 0.87 | ADORA2A (0.41) | ADORA2AADORA2BTP53GMNNNFKB1 | |
| Bromide SCHEMBL9672114 | 0.87 | ADORA2A (0.47) | ADORA2AADORA2BSLC29A1TP53GMNN | |
| SCHEMBL9673592 | 0.87 | ADORA2A (0.47) | ADORA2AADORA2BSLC29A1GMNNNFKB1 | |
| SCHEMBL9671821 | 0.87 | ADORA2A (0.51) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL9670797 | 0.86 | ADORA2A (0.42) | ADORA2AADORA2BSLC29A1TP53GMNN | |
| Bromide SCHEMBL9671949 | 0.86 | ADORA2A (0.50) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102873-A | Viricides | SOUTHERN RESEARCH INSTITUTE (US) | 1992-04-07 | — | — | US | claimed |
| US-5102873-A | Viricides | SOUTHERN RESEARCH INSTITUTE (US) | 1992-04-07 | — | — | US | disclosed |