Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.63 |
| ▸ | HTR1A | P08908 | 4/20 | 0.63 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271827 | 1.00 | SLC6A2 (0.63) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| SCHEMBL8271831 | 1.00 | SLC6A2 (0.63) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL4129951 | 0.98 | SLC6A2 (0.61) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL9132412 | 0.98 | SLC6A2 (0.61) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL4133478 | 0.98 | SLC6A2 (0.61) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| SCHEMBL1780546 | 0.89 | HRH1 (0.62) | SLC6A2HTR1AHTR2CSLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL4100905 | 0.88 | HRH1 (0.60) | SLC6A2HTR1AHTR2CSLC6A3SLC6A4 | |
| SCHEMBL2297425 | 0.85 | SLC6A2 (0.62) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL3330561 | 0.83 | HTR2C (0.67) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 | |
| SCHEMBL3175157 | 0.83 | HTR2C (0.67) | SLC6A2HTR1AHTR2CHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841758-B1 | SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LTD (GB) | 2009-11-18 | — | — | EP | disclosed |
| EP-0338331-B1 | 1,3 DISUBSTITUTED PYRROLIDINES | BAYER AG (DE) | 1992-10-21 | — | — | EP | disclosed |
| EP-0338331-A1 | 1,3 Disubstituted Pyrrolidines | BAYER AG (DE) | 1989-10-25 | — | — | EP | disclosed |
| US-4377582-A | HYPOTENSIVE AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4306065-A | HYPOTENSIVE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1981-12-15 | — | — | US | disclosed |
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |